Via di S. Teodoro, 48, 00186 Roma RM, Italy

Nestled amid gardens, this refined hotel in a converted, long-standing convent is a 12-minute walk from the nearest subway stop, and 1 km from the Roman Forum, a collection of ancient Roman remains. Modern rooms with wood accents and high ceilings feature Wi-Fi, flat-screen TVs and minibars. Upgraded room and suites add whirlpool tubs. Suites, some bi-level, have separate living areas. Room service is available. A breakfast buffet is served in a polished restaurant with vaulted ceilings and garden terrace seating; there's also a lobby bar. Other amenities include conference facilities.

Via Vittorio Veneto, 62, 00187 Roma RM, Italy

V. Giulia, 62, 00186 Roma RM, Italy

Set in a traditional building with stone foundations, this sleek hotel is 15 minutes' walk from the Pantheon and 1.8 km from the Sistine Chapel. Contemporary rooms with wood floors and marble bathrooms offer free Wi-Fi, flat-screen TVs and iPod docks, as well as minibars, and tea and coffeemakers. Some offer retro or reproduction artwork. Upgraded rooms include complimentary minibars, and suites add living areas with pull-out sofas. A free breakfast buffet is served in a bright bistro. Other amenities include a wine bar and a restaurant with a seasonal rooftop terrace. There's also a spa with a hot tub, a sauna and a fitness room.

Via Solferino, 6, 50123 Firenze FI, Italy

Via Ventisette Aprile, 52/R, 50129 Firenze FI, Italy

A 6-minute walk from Galleria dell'Accademia, this elegant hotel in a classic stone building is 11 minutes' walk from Florence Cathedral and 17 minutes' walk from Ponte Vecchio bridge. Featuring Wi-Fi, the warm, individually designed rooms with vintage Florentine decor offer flat-screen TVs, minifridges and desks. Some have canopy beds, sofabeds, and/or tea and coffeemakers. A breakfast buffet is served in a relaxed dining room or in-room. There's also a lounge with a wood-beamed ceiling.

Via de' Cerretani, 68, 50123 Firenze FI, Italy

A 4-minute walk from the Cathedral of Santa Maria del Fiore, this polished hotel in a 17th-century building is 1 km both from Renaissance art in the Uffizi Gallery and from medieval Ponte Vecchio. Refined rooms offer free Wi-Fi, flat-screen TVs and minibars, plus tea and coffeemaking equipment. They also include marble bathrooms and designer toiletries. Suites add separate living areas. Room service is available 24/7. Amenities include a business center and a sophisticated bar offering traditional Tuscan cuisine. A breakfast buffet is available for a fee.

Campo San Stae, 2070, 30135 Venezia VE, Italy

Adjacent to the San Stae vaporetto stop on the Grand Canal, this elegant 16th-century palace-turned-hotel is a 9-minute walk from the Rialto Bridge. Refined rooms feature traditional terrazzo or parquet floors, and stone or marble bathrooms. All provide Wi-Fi, flat-screen TVs and safes; some have canal views. Suites add living space, balconies and/or whirlpool tubs. Individual details include sloped wood-beamed ceilings, original 16th-century furniture and ornate chandeliers. Room service is available. Breakfast is available. Amenities consist of a polished bar and lounge areas.

Riva degli Schiavoni, 4149, 30122 Venezia VE, Italy

Offering Venetian Lagoon views, this premium hotel is an 8-minute walk from Saint Mark's Basilica, a 9-minute walk from Piazza San Marco and 2 km from the Grand Canal. Ornate rooms and suites with plush decor and antique furniture come with seating areas. Some include murals, 4-poster beds, fireplaces and/or lagoon views. There's a suite with a rooftop terrace; another features a hammam. Wi-Fi is available. Breakfast is available. There's a renowned restaurant, a garden terrace, and a refined cocktail bar that hosts seasonal tea ceremonies. A gallery has a collection of antiques.

Santa Croce 245, Giardini Papadopoli, 30135 Venezia VE, Italy

Set beside a canal, this upscale, chic hotel is a 2-minute walk from the nearest vaporetto stop and 1.8 km from the iconic, 12th-century Piazza San Marco. Elegant rooms styled in luxe, 18th-century Venetian decor include free Wi-Fi, flat-screen TVs, minibars and work desks. Suites are available, and room service is also offered. Amenities include an elegant restaurant with exposed stone walls and a glass-enclosed dining room, plus a refined bar and a winter garden.